Rilzabrutinib
Tier C — Watch / tradeRilzabrutinib
Targets：BTK
Brand：Wayrilz
Indications (approved)：Immune thrombocytopenic purpura
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| Rilza-001 | 2380-63-4Available | 1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| Rilza-002 | 151266-23-8Available | 3-iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| Rilza-003 | 143900-43-0Available | tert-butyl (R)-3-hydroxypiperidine-1-carboxylate |
| Rilza-004 | 461699-13-8Available | tert-butyl 3-(4-amino-3-iodo-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate |
| Rilza-005 | 1414356-30-1Available | 2-fluoro-4-phenoxyphenylboronic acid |
| Rilza-006 | 1414356-80-1Available | tert-butyl 3-(4-amino-3-(2-fluoro-4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate |
| Rilza-007 | 1414356-82-3Available | 3-(2-fluoro-4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| Rilza-008 | 1414356-84-5Available | 3-(3-(4-amino-3-(2-fluoro-4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-oxopropanenitrile |
| Rilza-009 | 1575591-71-7Available | 2-methyl-2-(4-(oxetan-3-yl)piperazin-1-yl)propanal |
| Rilza-010 | 121219-03-2Available | 4-bromo-3-fluorophenol |
| Rilza-011 | 98-80-6Available | phenylboronic acid |
| Rilza-012 | 1138557-58-0Available | 1-bromo-2-fluoro-4-phenoxybenzene |
| Rilza-013 | 13206-46-7Available | 2-bromo-2-methylpropanal |
| Rilza-014 | 1254115-23-5Available | 1-(oxetan-3-yl)piperazine |
Frequently asked questions
What are the approved indications of Rilzabrutinib?
Approved indications include: Immune thrombocytopenic purpura.
When does the Rilzabrutinib patent expire?
No public expiry year is available for Rilzabrutinib yet; this page updates once verified.
How many synthesis routes are recorded for Rilzabrutinib?
1 synthesis routes are recorded; the shortest is 9 steps with 79mg (Rilzabrutinib) total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Rilzabrutinib intermediates?
14 intermediate CAS of Rilzabrutinib are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Rilzabrutinib intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-10-22