Mifanertinib Maleate
Tier C — Watch / tradeMifanertinib Maleate
Targets:EGFR, HER2, EGFR 19del, EGFR L858R, EGFR T790M
Indications (approved):Non-small cell lung cancer
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| Mefatinib | 1639014-72-4 | (E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-(difluoromethoxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide |
| MEFATI-001 | 1417695-77-2 | N-(3-chloro-4-fluorophenyl)-7-(difluoromethoxy)-6-nitroquinazolin-4-amine |
| MEFATI-002 | 1417695-78-3 | N4-(3-chloro-4-fluorophenyl)-7-(difluoromethoxy)quinazoline-4,6-diamine |
| MEFATI-003 | 3095-95-2 | 2-(diethoxyphosphoryl)acetic acid |
| MEFATI-004 | 1639014-74-6 | diethyl (2-((4-((3-chloro-4-fluorophenyl)amino)-7-(difluoromethoxy)quinazolin-6-yl)amino)-2-oxoethyl)phosphonate |
Frequently asked questions
What are the approved indications of Mifanertinib Maleate?
Approved indications include: Non-small cell lung cancer.
When does the Mifanertinib Maleate patent expire?
No public expiry year is available for Mifanertinib Maleate yet; this page updates once verified.
How many synthesis routes are recorded for Mifanertinib Maleate?
1 synthesis routes are recorded; the shortest is 3 steps with 479 g total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Mifanertinib Maleate intermediates?
All intermediates in Mifanertinib Maleate routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for Mifanertinib Maleate intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-10-22