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Mifanertinib Maleate

Tier C — Watch / trade

Mifanertinib Maleate

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Originator
2025
First approval
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Expiry (public)
No sales data
Peak sales
Small molecule
Type

Targets:EGFR, HER2, EGFR 19del, EGFR L858R, EGFR T790M

Indications (approved):Non-small cell lung cancer

Regional status

US
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EU
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China
Approved
2025-10-21
Japan
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Synthetic routes & intermediates1 routes

Originator routes × 1Optimised (non-patent) × 0Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 3 · Total yield 479 g
Mefatinib1639014-72-4MEFATI-0011417695-77-2MEFATI-0021417695-78-3MEFATI-0033095-95-2MEFATI-0041639014-74-6API · Mifanertinib Maleate
CodeCAS No.Intermediate
Mefatinib1639014-72-4(E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-(difluoromethoxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide
MEFATI-0011417695-77-2N-(3-chloro-4-fluorophenyl)-7-(difluoromethoxy)-6-nitroquinazolin-4-amine
MEFATI-0021417695-78-3N4-(3-chloro-4-fluorophenyl)-7-(difluoromethoxy)quinazoline-4,6-diamine
MEFATI-0033095-95-22-(diethoxyphosphoryl)acetic acid
MEFATI-0041639014-74-6diethyl (2-((4-((3-chloro-4-fluorophenyl)amino)-7-(difluoromethoxy)quinazolin-6-yl)amino)-2-oxoethyl)phosphonate

Frequently asked questions

What are the approved indications of Mifanertinib Maleate?

Approved indications include: Non-small cell lung cancer.

When does the Mifanertinib Maleate patent expire?

No public expiry year is available for Mifanertinib Maleate yet; this page updates once verified.

How many synthesis routes are recorded for Mifanertinib Maleate?

1 synthesis routes are recorded; the shortest is 3 steps with 479 g total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Mifanertinib Maleate intermediates?

All intermediates in Mifanertinib Maleate routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.

How do I get a quote for Mifanertinib Maleate intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-10-22