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CAS 102029-44-7
(R)-4-(Phenylmethyl)-2-oxazolidinone(R)-4-benzyloxazolidin-2-one
Codes: (I)638294-21-a, MITI-015, IPAT-002, RIMI-003
Application context (from source-drug indications)
Systolic heart failureFinerenoneDiastolic heart failureFinerenoneHeart failureFinerenoneChronic renal impairmentFinerenoneDiabetic nephropathyFinerenoneType 2 diabetesFinerenoneType 2 diabetesMitiglinideDiabetesMitiglinideBreast cancerIpatasertib三阴性乳腺癌IpatasertibCastration-resistant prostate cancerIpatasertibProstate cancerIpatasertibPeritoneal cancerIpatasertibOvarian cancerIpatasertib大B细胞淋巴瘤RimiducidHodgkin's diseaseRimiducidNon-Hodgkin lymphomaRimiducid骨硬化症Rimiducid血红蛋白病Rimiducid血细胞减少症Rimiducid
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Finerenone | Tier C — Watch / trade | 2030 |
| Mitiglinide | Tier C — Watch / trade | - |
| Ipatasertib | Tier C — Watch / trade | - |
| Rimiducid | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(R)-4-(Phenylmethyl)-2-oxazolidinone→3-Hydroxy 3-butenoic acid beta-lactone→1-[(4R)-4-Benzyl-2-oxo-1,3-oxazolidin-3-yl]butane-1,3-dione→2-Methoxy-4-cyanobenzaldehyde→4-[2-[(4R)-4-Benzyl-2-oxo-1,3-oxazolidine-3-carbonyl]-3-oxobut-1-en-1-yl]-3-methoxybenzonitrile→4-Amino-5-methylpyridin-2(1H)-one→4-[3-[(4R)-4-Benzyl-2-oxo-1,3-oxazolidine-3-carbonyl]-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridin-4-yl]-3-methoxybenzonitrile→4-[(4S)-3-[(4R)-4-Benzyl-2-oxo-1,3-oxazolidine-3-carbonyl]-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridin-4-yl]-3-methoxybenzonitrile→1,1,1-Triethoxyethane→4-[(4S)-3-[(4R)-4-Benzyl-2-oxo-1,3-oxazolidine-3-carbonyl]-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridin-4-yl]-3-methoxybenzonitrile
(3aR,7aS)-octahydro-1H-isoindole→(S)-2-benzyl-4-((3aR,7aS)-octahydro-2H-isoindol-2-yl)-4-oxobutanoic acid→3-phenylpropanoic acid→(R)-4-benzyloxazolidin-2-one→(R)-4-benzyl-3-(3-phenylpropanoyl)oxazolidin-2-one→tert-butyl 2-bromoacetate→tert-butyl (S)-3-benzyl-4-((R)-4-benzyl-2-oxooxazolidin-3-yl)-4-oxobutanoate→(S)-3-benzyl-4-((R)-4-benzyl-2-oxooxazolidin-3-yl)-4-oxobutanoic acid→(S)-2-benzyl-1-((R)-4-benzyl-2-oxooxazolidin-3-yl)-4-((3aR,7aS)-octahydro-2H-isoindol-2-yl)butane-1,4-dione
2-(4-chlorophenyl)acetyl chloride→(R)-4-benzyloxazolidin-2-one→(R)-4-benzyl-3-(2-(4-chlorophenyl)acetyl)oxazolidin-2-one→tert-butyl isopropyl(methoxymethyl)carbamate→tert-butyl ((S)-3-((R)-4-benzyl-2-oxooxazolidin-3-yl)-2-(4-chlorophenyl)-3-oxopropyl)(isopropyl)carbamate→(S)-3-((tert-butoxycarbonyl)(isopropyl)amino)-2-(4-chlorophenyl)propanoic acid→(5R,7R)-5-methyl-4-(piperazin-1-yl)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-7-ol dihydrochloride→tert-butyl ((S)-2-(4-chlorophenyl)-3-(4-((5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazin-1-yl)-3-oxopropyl)(isopropyl)carbamate→(S)-2-(4-chlorophenyl)-1-(4-((5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazin-1-yl)-3-(isopropylamino)propan-1-one dihydrochloride
2-(3,4,5-trimethoxyphenyl)acetic acid→2-(3,4,5-trimethoxyphenyl)butanoic acid→(R)-4-benzyloxazolidin-2-one→(4R)-4-benzyl-3-(2-(3,4,5-trimethoxyphenyl)butanoyl)oxazolidin-2-one→(S)-2-(3,4,5-trimethoxyphenyl)butanoic acid→methyl (S)-piperidine-2-carboxylate→(S)-1-((S)-2-(3,4,5-trimethoxyphenyl)butanoyl)piperidine-2-carboxylic acid→tert-butyl (R)-2-(3-(3-(3,4-dimethoxyphenyl)-1-hydroxypropyl)phenoxy)acetate→(R)-1-(3-(2-(tert-butoxy)-2-oxoethoxy)phenyl)-3-(3,4-dimethoxyphenyl)propyl (S)-1-((S)-2-(3,4,5-trimethoxyphenyl)butanoyl)piperidine-2-carboxylate→3,4-dimethoxybenzaldehyde→1-(3-hydroxyphenyl)ethan-1-one→(E)-3-(3,4-dimethoxyphenyl)-1-(3-hydroxyphenyl)prop-2-en-1-one→3-(3,4-dimethoxyphenyl)-1-(3-hydroxyphenyl)propan-1-one→tert-butyl 2-(3-(3-(3,4-dimethoxyphenyl)propanoyl)phenoxy)acetate
Intermediates available on this site
Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.
| Supplier | Product | Price band | MOQ | Lead time | Qualifications | Action |
|---|---|---|---|---|---|---|
| Unibest Nantong cGMP Site | (R)-4-Benzyl-2-oxazolidinone Pharmaceutical Intermediates | On request | On request | On request | — |
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