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CAS 62-53-3
Aminobenzeneaniline
Codes: (V)819703-2-a, PERAM-031, SELT-005, Atorvastatin-049, IVAC-001, FENT-004, (I)91353-9-a, (I)91353-11-a, (XXVII)700647-1-c, NELF-013
Application context (from source-drug indications)
Gastrointestinal stromal tumourRipretinibTonic-clonic seizurePerampanel HydratePartial-onset seizurePerampanel HydrateEpilepsyPerampanel HydrateSeizurePerampanel HydratePlexiform neurofibromaSelumetinib sulfateNeurofibromatosis type ISelumetinib sulfateCardiac and vascular disordersAtorvastatin/Hydrochlorothiazide/Aspirin/EnalaprilHypertensionAtorvastatin/Hydrochlorothiazide/Aspirin/EnalaprilHyperlipidaemiaAtorvastatin/Hydrochlorothiazide/Aspirin/EnalaprilHeart diseaseAtorvastatin/Hydrochlorothiazide/Aspirin/EnalaprilCystic fibrosisIvacaftorChronic bronchitisIvacaftorChronic obstructive pulmonary diseaseIvacaftorSinusitisIvacaftorPainBupivacaine Hydrochloride/Fentanyl CitrateBack painDiclofenac Sodium/Eperisone HydrochlorideHyperlipidaemiaAtorvastatin strontiumSubarachnoid haemorrhageAtorvastatin strontiumHypertensionAtorvastatin strontiumPainFentanylDisease of prematurityFentanylPostoperative painFentanylCancer painFentanylSolid tumourFentanylSurgical painFentanylOsteoarthritisDiclofenac SodiumRheumatoid arthritisDiclofenac SodiumAnkylosing spondylitisDiclofenac SodiumCommon bile duct diseaseDiclofenac SodiumDental pulp diseaseDiclofenac SodiumArthritisDiclofenac Sodium蠕形螨性睑缘炎Lotilaner螨虫感染Lotilaner莱姆病LotilanerRosaceaLotilaner睑板腺功能障碍LotilanerHIV infectionNelfinavir MesylateMyelofibrosisNelfinavir Mesylate子宫颈功能不全Nelfinavir MesylateSystemic lupus erythematosusNelfinavir MesylateNon-small cell lung cancerNelfinavir Mesylate巨细胞病毒性视网膜炎Nelfinavir Mesylate
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Ripretinib | Tier C — Watch / trade | 2032 |
| Perampanel Hydrate | Tier C — Watch / trade | 2028 |
| Selumetinib sulfate | Tier C — Watch / trade | 2032 |
| Atorvastatin/Hydrochlorothiazide/Aspirin/Enalapril | Tier C — Watch / trade | - |
| Ivacaftor | Tier B — Position early | - |
| Bupivacaine Hydrochloride/Fentanyl Citrate | Tier C — Watch / trade | - |
| Diclofenac Sodium/Eperisone Hydrochloride | Tier C — Watch / trade | - |
| Atorvastatin strontium | Tier C — Watch / trade | - |
| Fentanyl | Tier C — Watch / trade | - |
| Diclofenac Sodium | Tier C — Watch / trade | - |
| Lotilaner | Tier C — Watch / trade | - |
| Nelfinavir Mesylate | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
Methyl (2-bromo-4-fluoro-5-nitrophenyl)acetate→6-Chloro-4-nitropyridine-3-carbaldehyde→Methyl (2Z)-2-(2-bromo-4-fluoro-5-nitrophenyl)-3-(6-chloro-4-nitropyridin-3-yl)prop-2-enoate→3-(5-Amino-2-bromo-4-fluorophenyl)-7-chloro-1,6-naphthyridin-2(1H)-one→Aminobenzene→1,1,1-Trichloromethanol 1,1'-carbonate→N-[4-Bromo-5-(7-chloro-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-2-fluorophenyl]-N'-phenylurea→1-Iodoethane→N-[4-Bromo-5-(7-chloro-1-ethyl-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-2-fluorophenyl]-N'-phenylurea→Aminomethane
2,3,4-trifluorobenzoic acid→2,3,4-trifluoro-5-nitrobenzoic acid→4-amino-2,3-difluoro-5-nitrobenzoic acid→methyl 4-amino-2,3-difluoro-5-nitrobenzoate→aniline→SELT-006→SELT-007→SELT-008→SELT-009→SELT-010→SELT-011→methyl 2-((2-fluoro-4-iodophenyl)amino)-1,5-dimethyl-6-oxo-1,6-dihydropyridine-3-carboxylate→SELT-013
4-Methyl-3-oxopentanoic acid methyl ester→4-Methyl-3-oxopentanoic acid 4-methoxybenzyl ester→Benzaldehyde→2-Benzylidene-4-methyl-3-oxopentanoic acid 4-methoxybenzyl ester→1-[3(R)-[tert-Butyl(dimethyl)silyloxy]-5-hydroxypentyl]-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid→(4-Fluorophenyl)methanone→2-[2-(4-Fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxopentanoic acid 4-methoxybenzyl ester→5-Amino-3(R)-[tert-butyl(dimethyl)silyloxy]pentan-1-ol→1-[3(R)-[tert-Butyl(dimethyl)silyloxy]-5-hydroxypentyl]-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid 4-methoxybenzyl ester→Aminobenzene→1-[3(R)-[tert-butyl(dimethyl)silyloxy]-5-hydroxypentyl]-5-(4-fluorophenyl)-2-isopropyl-N,4-diphenyl-1H-pyrrole-3-carboxamide→1-[3(R)-[tert-Butyl(dimethyl)silyloxy]-5-oxopentyl]-5-(4-fluorophenyl)-2-isopropyl-N,4-diphenyl-1H-pyrrole-3-carboxamide
aniline→diethyl 2-(ethoxymethylene)malonate→diethyl 2-((phenylamino)methylene)malonate→ethyl 4-oxo-1,4-dihydroquinoline-3-carboxylate→4-oxo-1,4-dihydroquinoline-3-carboxylic acid→5-amino-2,4-di-tert-butylphenol→2,4-di-tert-butylphenol→2,4-di-tert-butylphenyl methyl carbonate→2,4-di-tert-butyl-5-nitrophenyl methyl carbonate→2,4-di-tert-butyl-5-nitrophenol
Intermediates available on this site
Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.
| Supplier | Product | Price band | MOQ | Lead time | Qualifications | Action |
|---|---|---|---|---|---|---|
| Unibest Nantong cGMP Site | 2-bromo-3-methyl-5-acetylthiophene Pharmaceutical Intermediates | On request | On request | On request | — | |
| Unibest Taizhou GMP-like Site | methyl 5-acetyl-3-methylthiophene-2-carboxylate Pharmaceutical Intermediates | On request | On request | On request | — | |
| Qualified Partner — East China API Works | 5-acetyl-3-methyl-2-Thiophenecarboxylic acid Pharmaceutical Intermediates | On request | On request | On request | — |
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.