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CAS 66722-44-9
(±)-1-[4-[2-(Isopropoxy)ethoxymethyl]phenoxy]-3-(isopropylamino)propan-2-ol
Codes: Bisoprolol-014
Application context (from source-drug indications)
HypertensionAmlodipine Besylate/Bisoprolol FumarateEssential hypertensionAmlodipine Besylate/Bisoprolol FumarateHypertensionBisoprolol FumarateAngina pectorisBisoprolol FumarateChronic obstructive pulmonary diseaseBisoprolol FumarateCardiac and vascular disordersBisoprolol FumarateAcute coronary syndromeBisoprolol FumarateFastingBisoprolol Fumarate
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Amlodipine Besylate/Bisoprolol Fumarate | Tier C — Watch / trade | - |
| Bisoprolol Fumarate | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
4-Hydroxybenzyl alcohol→4-[(2-Isopropoxyethoxy)methyl]phenol→2-(4-{[2-(propan-2-yloxy)ethoxy]methyl}phenoxymethyl)oxirane→(±)-1-[4-[2-(Isopropoxy)ethoxymethyl]phenoxy]-3-(isopropylamino)propan-2-ol→(+/-)-2-(Chloromethyl)oxirane→Propan-2-amine→Isopropylglycol
3-(Isopropylamino)propane-1,2-diol→Methyl carbonate→5-(Hydroxymethyl)-3-isopropyloxazolidin-2-one→Benzenesulfonic acid 3-isopropyl-2-oxooxazolidin-5-ylmethyl ester→4-(3-Isopropyl-2-oxooxazolidin-5-ylmethoxy)benzaldehyde→5-[4-(Hydroxymethyl)phenoxymethyl]-3-isopropyloxazolidin-2-one→2-Isopropoxyethanol→4-Hydroxybenzaldehyde→(±)-1-[4-[2-(Isopropoxy)ethoxymethyl]phenoxy]-3-(isopropylamino)propan-2-ol
4-[(2-Isopropoxyethoxy)methyl]phenol→3-(Isopropylamino)propane-1,2-diol→(±)-1-[4-[2-(Isopropoxy)ethoxymethyl]phenoxy]-3-(isopropylamino)propan-2-ol
4-Hydroxybenzyl alcohol→4-[(2-Isopropoxyethoxy)methyl]phenol→2-(4-{[2-(propan-2-yloxy)ethoxy]methyl}phenoxymethyl)oxirane→(±)-1-[4-[2-(Isopropoxy)ethoxymethyl]phenoxy]-3-(isopropylamino)propan-2-ol→(+/-)-2-(Chloromethyl)oxirane→Propan-2-amine→Isopropylglycol
3-(Isopropylamino)propane-1,2-diol→Methyl carbonate→5-(Hydroxymethyl)-3-isopropyloxazolidin-2-one→Benzenesulfonic acid 3-isopropyl-2-oxooxazolidin-5-ylmethyl ester→4-(3-Isopropyl-2-oxooxazolidin-5-ylmethoxy)benzaldehyde→5-[4-(Hydroxymethyl)phenoxymethyl]-3-isopropyloxazolidin-2-one→2-Isopropoxyethanol→4-Hydroxybenzaldehyde→(±)-1-[4-[2-(Isopropoxy)ethoxymethyl]phenoxy]-3-(isopropylamino)propan-2-ol
Intermediates available on this site
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