Fosnetupitant
Tier C — Watch / tradeFosnetupitant
Targets：NK1R
Brand：Arokaris
Indications (approved)：Chemotherapy-induced nausea and vomiting
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| FOSNE-007 | 342417-01-0 | 6-(4-methylpiperazin-1-yl)-4-(o-tolyl)nicotinamide |
| FOSNE-008 | 290297-24-4 | - |
| FOSNE-009 | 342417-02-1 | methyl (6-(4-methylpiperazin-1-yl)-4-(o-tolyl)pyridin-3-yl)carbamate |
| FOSNE-010 | 290297-25-5 | N-methyl-6-(4-methylpiperazin-1-yl)-4-(o-tolyl)pyridin-3-amine |
| FOSNE-011 | 289686-69-7Available | 2-(3,5-bis(trifluoromethyl)phenyl)-2-methylpropanoyl chloride |
| FOSNE-012 | 290297-26-6 | - |
| FOSNE-013 | 229625-50-7Available | di-tert-butyl (chloromethyl) phosphate |
| FOSNE-014 | 1703749-32-9 | - |
| FOSNE-015 | 289686-70-0Available | 2-(3,5-bis(trifluoromethyl)phenyl)-2-methylpropanoic acid |
| FOSNE-016 | 13086-84-5 | - |
| FOSNE-017 | 33494-80-3 | - |
| FOSNE-018 | 33494-81-4 | - |
| FOSNE-019 | 34075-24-6 | - |
| Fosnetupitant | - | - |
| FOSNE-001 | 5326-23-8 | 6-chloronicotinic acid |
| FOSNE-002 | 33872-80-9 | o-tolylmagnesium chloride |
| FOSNE-003 | 342416-99-3 | - |
| FOSNE-004 | - | - |
| FOSNE-005 | 342417-00-9 | - |
| FOSNE-006 | 109-01-3Available | 1-methylpiperazine |
Frequently asked questions
What are the approved indications of Fosnetupitant?
Approved indications include: Chemotherapy-induced nausea and vomiting.
When does the Fosnetupitant patent expire?
No public expiry year is available for Fosnetupitant yet; this page updates once verified.
How many synthesis routes are recorded for Fosnetupitant?
1 synthesis routes are recorded; the shortest is 15 steps with 15 g total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Fosnetupitant intermediates?
4 intermediate CAS of Fosnetupitant are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Fosnetupitant intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-10-22