Vornorexant
Tier C — Watch / tradeVornorexant
Targets：OX2R, OX1R
Brand：Vorzzz, ボルズィ
Indications (approved)：Insomnia and sleep disorders
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| Vornorexant-001 | 156-87-6 | 3-aminopropan-1-ol |
| Vornorexant-002 | 298-12-4Available | 2-oxoacetic acid |
| Vornorexant-003 | - | 1,3-oxazinane-2-carboxylic acid |
| Vornorexant-004 | 501-53-1Available | benzyl carbonochloridate |
| Vornorexant-005 | - | 3-((benzyloxy)carbonyl)-1,3-oxazinane-2-carboxylic acid |
| Vornorexant-006 | 2549-14-6 | (R)-2-amino-2-phenylethan-1-ol |
| Vornorexant-007 | - | (S)-3-((benzyloxy)carbonyl)-1,3-oxazinane-2-carboxylic acid, (R)-2-amino-2-phenylethan-1-ol |
| Vornorexant-008 | - | (S)-3-((benzyloxy)carbonyl)-1,3-oxazinane-2-carboxylic acid |
| Vornorexant-009 | - | 3-benzyl 2-methyl (S)-1,3-oxazinane-2,3-dicarboxylate |
| Vornorexant-010 | - | methyl (S)-1,3-oxazinane-2-carboxylate |
| Vornorexant-011 | 1104546-96-4 | 5-methyl-2-(2H-1,2,3-triazol-2-yl)benzoyl chloride |
| Vornorexant-012 | - | methyl (S)-3-(5-methyl-2-(2H-1,2,3-triazol-2-yl)benzoyl)-1,3-oxazinane-2-carboxylate |
| Vornorexant-013 | - | (S)-(2-(hydroxymethyl)-1,3-oxazinan-3-yl)(5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl)methanone |
| Vornorexant-014 | - | 5-fluoro-2-(1-(methylsulfonyl)-1H-pyrazol-3-yl)pyridine |
| Vornorexant-015 | 449758-17-2 | 1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole |
| Vornorexant-016 | 31301-51-6 | 2-chloro-5-fluoropyridine |
| Vornorexant-017 | 1381971-84-1 | 5-fluoro-2-(1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazol-5-yl)pyridine |
| Vornorexant-018 | 1382035-54-2 | 5-fluoro-2-(1H-pyrazol-3-yl)pyridine |
| Vornorexant-019 | 956317-36-5Available | 5-methyl-2-(2H-1,2,3-triazol-2-yl)benzoic acid |
Frequently asked questions
What are the approved indications of Vornorexant?
Approved indications include: Insomnia and sleep disorders.
When does the Vornorexant patent expire?
No public expiry year is available for Vornorexant yet; this page updates once verified.
How many synthesis routes are recorded for Vornorexant?
1 synthesis routes are recorded; the shortest is 9 steps with / total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Vornorexant intermediates?
3 intermediate CAS of Vornorexant are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Vornorexant intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-10-22